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SHYAM SUNDAR
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Educational Qualifications :
M.B.B.S. (Medical Sciences), Institute of Medical Sciences
Banaras Hindu University (BHU), Varanasi, India 1976
M.D. (Medicine) Institute of Medical Sciences BHU, , Varanasi, India 1981
Employment
| Name of Employer / Institution |
Dates
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Designation
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Institute of Medical Sciences
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Jan, 1997 - till date
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Professor of Medicine
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April 2001 - April 2004
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Head, Department of MedicineBanaras Hindu
University
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Apr, 1990 - Jan, 1997
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Reader in Medicine
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Mar. 1981 - Apr; 1990
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Lecturer in Medicine
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Honorary Chief Investigator -
Kala-azar Medical Research Center, Rambag Road,
Muzaffarpur
Fellowships:
| Fellow (FRCP) |
Royal College of Physicians, London |
| Fellow (FAMS) |
National Academy of Medical Sciences,
India |
| Fellow (FNASc) |
National Academy of Sciences, India |
| -Fellow (FASc) |
Indian Academy of Sciences, India |
| Fellow (FNA) |
Indian National Science Academy, India |
AWARDS
| Netaji Oration |
Association of Physicians of India, 2006 |
| Best Teacher Award |
Indian Medical Association, Varanasi |
| DB Chandra Oration |
MLN Medical College Alumni Assoc., Allahabad |
| Ranbaxy Research Award |
Ranbaxy Science Foundation, 2002 |
| Dr Rajendra Prasad Memorial Oration |
RMR Institute of Medical Sciences (ICMR)
2001 |
| Dr Kamla Menon Medical |
Indian Council Of Medical Research 1996 |
Research Award
| Dr Coelho Memorial Oration |
Association Of Physicians Of India, 1995 |
| Dr. M. J. Shah Memorial Award |
Association of Physicians of India, 1994 |
| Dr. N. N. Gupta Award |
Associations of Physicians
of India (U.P. Chapter), 1993 |
| Author: |
Davidson's Principle and Practice
of Medicine, 20th Edition, 2006 |
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Conn's Current Therapy, 2002 |
| Important Media Coverage of the Work:
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Exclusive television documentaries |
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Discovery Channel |
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BBC World |
RESEARCH GRANTS
ONGOING:
National Institute of Allergy and Infectious Diseases,
National Institutes of Health, USA,
Visceral Leishmaniasis in Bihar State, India
- 14.6 Crores
Infectious Diseases Rsearch Institute/Bill & Melinda
Gates Foundation
A phase I, open-label, dose-escalating study to evaluate the safety, tolerability,
and immunogenicity of the Leish-111f + MPL-SE vaccine (recombinant three-antigen
Leishmania polyprotein with adjuvant MPL-SE) in healthy adults in india
- 65 Lakhs
European Commission:
Efficacy, acceptability and cost-effectiveness of long lasting insecticide
treated nets in the prevention of Kala-azar - 2.2 Crores
World Health Organisation/Tropical Diseases Research:
A Evaluation of Health System in Delivering Health Care in Visceral Leishmaniasis
- 20 Lakhs
Indian Council of Medical Research
Comparative Evaluation of PCR Primers In Diagnosis and Prognosis of Indian
Visceral Leishmaniasis (VL) and Post Kala-Azar Dermal Leishmaniasis (PKDL)
- 20 Lakhs
COMPLETED
World Health Organisation/Tropical Diseases
Research
A Phase III Multicenter, Randomized, Controlled, Clinical
Trial to Assess the Safety and Efficacy of injectable Paromomycin in Patients
with Visceral Leishmaniasis
Field Evaluation of novel diagnostic tests for Visceral
Leishmaniasis: freeze dried DAT, rK39, rK26 dipsticks and KAtex (latex
agglutination urine test)
Visceral Leishmaniasis and PKDL in India: New Therapeutic,
Immunologic and Diagnostic Studies, and Site Preparation for Vaccine Trial
- a multiinstitutional project involving BHU, CDRI, IICB and RMRI (Project
Leader - Dr Shyam Sundar)
"Treatment of visceral leishmaniasis with the orally
administrable agent miltefosine: a rising dose, phase II trial"
"Immunochemotherapy for visceral leishmaniasis interferon-gamma
plus antimony"
A Phase III Clinical trial to assess efficacy and safety
of orally administered miltefosine in children with visceral leishmaniasis
A Study of HIV/VL Co-infection
A Phase III Clinical trial to assess efficacy and safety
of orally administered miltefosine in patients with visceral leishmaniasis
with Control group: Amphotericin B
A phase II trial of short course amphotericin B and Fat
emulsion in the treatment of Indian kala-azar
A multicenter phase II trial of miltefosine in Indian Visceral
Leishmaniasis.
A Phase II Clinical trial to assess efficacy and safety
of orally administered miltefosine in children with visceral leishmaniasis
Joint Indo-US Vaccine Action Programme.
"Immunologic and parasitologic studies
of Indian Visceral Leishmaniasis"
NIH/National Institute of Allergy and Infectious Diseases
Bethesda, MD, USA AND DEPARTMENT OF BIOTECHNOLOGY, GOVT OF INDIA
Rockefeller Foundation, New York, USA :
"Immunochemotherapy
for Indian visceral leishmaniasis: randomized controlled three-arm trial
of treatment with 30 days of antimony alone vs. 30 days of antimony plus
interferon- vs. 15 days of antimony plus interferon-t."
Indian Council of Medical Research :
"Effect of recombinant
human gamma interferon therapy in antimony resistant kala-azar - a clinical
and immunological study".
TRAINING FELLOWSHIP ABROAD
| UGC foreign Travel Fellowship for training
at The New York Hospital, New York, USA |
University Grants Commision,1993 |
| AIDS Training fellowship,Memorial Sloan
Ketering Hospital, New York, USA |
Infectious Diseases Society Of America,
1994 |
| WHO Workshop at CASABLANCA, Moracco |
WHO/TDR & NIH/NIAID USA Sponsored
typing workshop on leishmania 1995 |
| WHO/UNAIDS Workshopat Mae
Sot, Thailand Clinical Monitors |
Training Workshop on Good
for Clinical Practices (GCP) fromAsian Countries, 1999 |
WHO Workshop
at Addis Ababa,Ehiopita |
WHO/CTD Sponsored - HIV/Visceral Leishmaniasis
Co-infection Voluntary Counselling and Training, 1999 |
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Member & Fellow
| Fellow (FNA) |
Indian National Science Academy,
India |
| Fellow (FRCP) |
Royal College of Physicians, London |
| Fellow (FASc) |
Indian Academy of Sciences, India |
| Fellow (FNASc) |
National Academy of Sciences, India |
| Fellow (FAMS) |
National Academy of Medical Sciences,
India |
| Fellow (FICP) |
Indian College of Physicians |
| Member |
American Society of Tropical Medicine
& Hygeine |
| Member |
Indian Society of Hematology and
Blood Transfusion |
| Member |
Indian Geriatric Society |
| Member |
Assoication of Physicians of India |
Memberships of important :
Committees , Advisory Groups,
Commissions etc. Past and present.
| Member |
Scientific Working
Group of Leishmaniasis, TDR/WHO, Geneva 2004 |
| Advisor |
DNDi (Drugs for Neglected Diseases Initiative),
Geneva |
| Member |
AmBisome Consultative Group, WHO, Geneva
2005 |
| Advisor |
World Health Organization, SEARO, New
Delhi |
| Chairman |
Expert group on Diagnosis and Treatment
of Kala-azar, Govt. of India |
| Advisor |
Government of Nepal Expert Committee on
leishmaniasis |
| Member, |
Leishmaniasis Reference Group, World Health
Organization/TDR,
Geneva, Switzerland |
| Technical Expert |
For leishmaniasis,Indian Council of Medical
Research |
| Member |
Project Review Committee, Indian Council
of Medical Research |
| Expert |
Technical committee on Antiretroviral
Therapy, NACO, Govt. of India |
| Expert |
Technical committee on Opportunistic Infections
in HIV infection, NACO, Govt. of India |
| Member, PDT of Miltefosine |
World Health Organization/TDR, Geneva,
Switzerland |
| Member, PDT of Aminosidine |
World Health Organization/TDR, Geneva,
Switzerland |
| Member, |
Scientific Advisory Institute of One World
Health, San Francisco, USA
Committee |
| Former Editor |
International Journal of Infectious Diseases,
New York, USA. |
| Asst Editor, |
Journal of the Assoiciation of Physicians
of India |
| Member,Scientific Advisory Committee |
Institute of Pathology, New Delhi |
| Member, Scientific Advisory Committee |
Rajendra Memorial Institute of Medical
Sciences,
Patna |
| Member, Governing Body, |
Association of Physicians of India,
(UP Chapter) 1994-96. |
| Member |
Indian Society for Communicable Diseases |
| Member |
Indian Medical Associaion |
| Member |
American Society of Tropical Medicine
and Hygiene, USA |
Organised International/national CME/Updates/Conferences:
1. Org. Secretary, International
Symposium on visceral leishmaniasis, 1996.
2. TDR/WHO sponsored International meeting on Control of
Visceral Leishmaniasis in India, 1999
3. WHO sponsored Training Workshop on Management of Kala-azar
for Physicians and Pediatricians of Nepal, 1999
4. WHO/TDR sponsored GCP (Good Clinical Practice) and Good
Clincal Laboratory Practice training course, 2001
5. Coordinator - Seminar on Indian Perspectives in Tropical
Diseases, 2002
6. Organising Secretary, Annual Conference of the Association
of Physicians of India - 2003
7. WHO/TDR meeting on Implementation
Past and Present Collaborators:
NATIONAL
1. Dr Neeloo Singh, Dr Neena Goyal, Division of Biochemistry,
Central Drug Research Institute, Lucknow
2. Dr JC Katiyar, Dr Suman Gupta and Dr Anuradha Dube,
Division of Parasitology, Central Drug Research Institute, Lucknow
3. Dr VK Vinayak, Deparatment of Experimental Medicine,
Post Graduate Institute of Medical Education and Research, Chandigarh.
4. Dr Sarman Singh, Department of Laboratory Medicine,
All India Institute of Medical Sciences, New Delhi
5. Dr AN Bhaduri, Dr Santu Bandopadhyay, Dr Chitra Mandal,
Indian Institute of Chemical Biology, Calcutta.
6. Dr R Madhubala, School of Life Sciences, Jawaharlal
Nehru University, New Delhi
7. Dr Lalit Garg, National Institute of Immunology, New
Delhi
8. Dr SK Kar, Rajendra Memorial Institute of Medical Sciences,
Patna
INTERNATIONAL
9. Prof J Blackwell, Director,
Cambridge Institute for Medical Research, Cmbridge, UK
10. Prof Marleen Boelaert, Institute of Tropical Medicine,
Antwerp, Belgium
11. Dr Richard T Kenney, Laboratory of Parasitic Biology,
Center for Biologics Research, FDA, Bethesda, Maryland, USA
12. Dr H W Murray, Professor of Medicine, Ex-Chief, Infectious
Diseases, Cornell University Medical College and the New York Hospital,
1300 York Avenue, New York, NY 10021 USA
13. Dr. J D Berman, Chief, Division of Experimental Therapeutics,
Walter-Reed Army Institute of Research, Washington, USA
14. Dr KC Carter, Departmnent of Immunology, University
of Stathclyde, Glasgow, UK
15. Dr Farrokh Modabber, Infectious Diseases Research Institute,
Seattle, USA
16. Dr SG Reed, Professor of Microbiology, Chief Scientific
Advisor, Corixa Corporation, Seattle, USA
17. Dr KP Chang, Professor of Microbiology, Chicago University,
Chicago, Illinois
18. Dr Marc Oullete, Centre de Recherche en Infecitologie
du Center Hospitalier de L 'Universite, Laval, Quebec, Canada
19. Dr Greg Matlewski, Institute of Parasitology, McGill
University, Montreal Canada
20. Dr Peter Walden, Humboldt University, Berlin, Germany
REVIEWER/EXPERT
1. The Lancet
2. British Medical Journal
3. Wellcome Trust, London, U. K.
4. Israel Science Foundation, Jerusalem, Israel
5. Indian Council of Medical Research, New Delhi
6. Department of Biotechnology, Government of India
7. Department of Science and Technology, Government of India
8. Lancet Infectious Disease, UK
9. Clinical Infectious Diseases, USA
10. Infection and Immunity, USA
11. Antimicrobial Agents Chemotherapy, USA
12. Expert Review of Anti-infective Therapy, UK
13. Bull World Health Organisation, Geneva, Switzerland
14. International Journal of Infectious Diseases, New York, USA
15. Acta Tropica, Belgium
16. Trnasactions of the Royal Society of Tropical Medicine and Hygiene,
UK
17. Experimental Parasitology, USA
18. Tropical Medicine & International Health, London, UK
19. Medical Science Monitor, USA
20. Parasite, JOUR-EN-JOSAS, France
21. Expert Opinion on Pharmacotherapy, London, UK
22. Expert Review of Anti-infective Therapy
23. Journal of Association of Physicians of India, Mumbai
24. Journal of Postgraduate Medicine, Mumbai
25. Journal of Parasitic Diseases, Chandigarh
26. Indian Journal of Dermato. Lepro. & Venereology
27. Indian Journal of Preventive & Social Medicine
28. Journal of Internal Medicine of India
29. Immunology
30. Tropical Doctor
31. Diagnostic Microbiology Infectious Diseases, USA
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